Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6269700 | 0.86 | ALDH1A1 (0.36) | MAPTTSHRHSD17B10ALDH1A1KDM4E | |
| SCHEMBL6269237 | 0.86 | LMNA (0.40) | ALOX15MAPK1MAPTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8316265 | 0.85 | LMNA (0.40) | ALOX15MAPK1MAPTNPC1RAB9A | |
| SCHEMBL8313997 | 0.83 | MAPT (0.49) | MAPTTSHRSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8314899 | 0.82 | ALDH1A1 (0.36) | ALPGMAPTTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL6268793 | 0.82 | ALDH1A1 (0.33) | ALPGMAPTHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8313550 | 0.81 | ALDH1A1 (0.35) | ALPGALOX15MAPTNPC1POLB | |
| SCHEMBL6269249 | 0.80 | MLYCD (0.32) | MAPTPOLBHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8316142 | 0.79 | KMT2A (0.35) | MAPTPOLBALDH1A1KDM4EKMT2A | |
| SCHEMBL8313695 | 0.72 | KDM4E (0.34) | ALPGMAPTNPC1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0632033-B1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| US-5646308-A | POTASSIUM CHANNEL ACTIVATORS USED AS ANTIASTHMATICS, ANTIEPILEPTICS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0632033-A1 | NOVEL BENZOPYRAN DERIVATIVE | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1995-01-04 | — | — | EP | disclosed |