Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317737 | 0.87 | LMNA (0.55) | LMNAMAPTMDM4MDM2TTR | |
| SCHEMBL8313475 | 0.85 | ALDH1A1 (0.48) | LMNAMAPTNR1H4ALDH1A1MEN1 | |
| SCHEMBL8320373 | 0.83 | HDAC1 (0.57) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8317483 | 0.80 | ALDH1A1 (0.52) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8321364 | 0.78 | MAPT (0.50) | LMNAMAPTMDM4MDM2ALDH1A1 | |
| SCHEMBL8317750 | 0.76 | ALDH1A1 (0.59) | LMNAMAPTALDH1A1MAOBMEN1 | |
| SCHEMBL28161744 | 0.75 | TTR (0.57) | MAPTTTRDPP4ALDH1A1MAOB | |
| SCHEMBL13957063 | 0.74 | CA12 (0.69) | LMNAMAPTTTRDPP4ALDH1A1 | |
| SCHEMBL10851526 | 0.74 | CA12 (0.69) | LMNAMAPTTTRDPP4ALDH1A1 | |
| SCHEMBL10888420 | 0.74 | CA12 (0.69) | LMNAMAPTTTRDPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |