Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 4/20 | 0.43 |
| ▸ | ACACA | Q13085 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317750 | 0.89 | ALDH1A1 (0.59) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8321251 | 0.88 | LMNA (0.55) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8314172 | 0.87 | LMNA (0.47) | LMNAMDM4MAPTMDM2ALDH1A1 | |
| SCHEMBL8324894 | 0.81 | KMT2A (0.50) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL9599969 | 0.77 | KDM4E (0.74) | ALDH1A1SMN1; SMN2KDM4ETTRDPP4 | |
| SCHEMBL9599975 | 0.77 | KDM4E (0.74) | ALDH1A1SMN1; SMN2KDM4ETTRDPP4 | |
| SCHEMBL8320461 | 0.76 | EGFR (0.52) | LMNAMAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28161744 | 0.76 | TTR (0.57) | MAPTALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL13120952 | 0.75 | TTR (0.56) | MAPTALDH1A1SMN1; SMN2HTTKDM4E | |
| SCHEMBL1959915 | 0.74 | CA12 (0.71) | MAPTALDH1A1SMN1; SMN2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |