Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ACACB | O00763 | 4/20 | 0.45 |
| ▸ | ACACA | Q13085 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321251 | 0.89 | LMNA (0.55) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL8317737 | 0.89 | LMNA (0.55) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL8322075 | 0.83 | RXRA (0.46) | ALDH1A1KDM4EHTTKMT2AACACB | |
| SCHEMBL8313475 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL8324894 | 0.81 | KMT2A (0.50) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL8320461 | 0.80 | EGFR (0.52) | ALDH1A1SMN1; SMN2KDM4ELMNAHTT | |
| SCHEMBL8314172 | 0.76 | LMNA (0.47) | ALDH1A1SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL3079558 | 0.76 | KDM4E (1.00) | ALDH1A1SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL764029 | 0.76 | KDM4E (1.00) | ALDH1A1SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL1160848 | 0.75 | KDM4E (0.72) | ALDH1A1SMN1; SMN2KDM4EPOLBEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071401-A2 | HYDROXAMIC ACID DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS (HDCA) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-26 | — | — | WO | disclosed |