Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315643 | 0.93 | CHRM2 (0.52) | CHRM2 | |
| SCHEMBL8314516 | 0.82 | CHRM2 (0.52) | CHRM2 | |
| SCHEMBL8319668 | 0.80 | CHRM2 (0.52) | CHRM2 | |
| SCHEMBL8312932 | 0.79 | CHRM2 (0.55) | CHRM2 | |
| SCHEMBL8313975 | 0.75 | CHRM2 (0.49) | CHRM2 | |
| SCHEMBL8314793 | 0.73 | HRH3 (0.55) | CHRM2 | |
| SCHEMBL8313001 | 0.73 | MEN1 (0.45) | CHRM2 | |
| SCHEMBL8314512 | 0.72 | CHRM2 (0.47) | CHRM2 | |
| SCHEMBL8315477 | 0.70 | ALDH1A1 (0.51) | CHRM2 | |
| SCHEMBL8097555 | 0.63 | RAB9A (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004066960-A2 | COMBINATION OF H1, H3 AND H4 RECEPTOR ANTAGONISTS FOR TREATMENT OF ALLERGIC AND NON-ALLERGIC PULMONARY INFLAMMATION, CONGESTION AND ALLERGIC RHINITIS | SCHERING CORPORATION (US) | 2004-08-12 | — | — | WO | disclosed |