Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311410 | 0.88 | TAS1R3 (0.47) | CYP1A2RAB9ANPC1KMT2ALMNA | |
| SCHEMBL8317110 | 0.86 | MAPT (0.43) | CYP1A2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8313214 | 0.86 | TP53 (0.47) | RAB9AALDH1A1LMNAMAPTTP53 | |
| SCHEMBL8317248 | 0.85 | PTGS2 (0.52) | CYP1A2RAB9ASMN1; SMN2ALDH1A1PTGS2 | |
| SCHEMBL8313443 | 0.83 | ALDH1A1 (0.54) | CYP1A2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8313869 | 0.83 | RAB9A (0.42) | CYP1A2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8313931 | 0.82 | RAB9A (0.45) | CYP1A2RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8313640 | 0.79 | POLB (0.54) | CYP1A2RAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL8315616 | 0.79 | MAPT (0.52) | CYP1A2RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL8310460 | 0.79 | SMN1; SMN2 (0.47) | CYP1A2RAB9ANPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891332-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER INC. (US) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997036871-A1 | 6-PHENYLPYRIDYL-2-AMINE DERIVATIVES | PFIZER INC. (US) | 1997-10-09 | — | — | WO | disclosed |