Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323222 | 0.85 | ALDH1A1 (0.62) | ALDH1A1ALOX15KDM4EHPGDMAPT | |
| SCHEMBL9800425 | 0.84 | KDM4E (0.50) | ALDH1A1ALOX15KDM4EHPGDGAA | |
| SCHEMBL9315414 | 0.78 | SMN1; SMN2 (0.56) | ALDH1A1ALOX15KDM4EHPGDMAPT | |
| SCHEMBL8322828 | 0.78 | KDM4E (0.51) | ALDH1A1ALOX15KDM4EHPGDMAPT | |
| SCHEMBL8661094 | 0.78 | ALDH1A1 (0.50) | ALDH1A1ALOX15KDM4EHPGDMAPT | |
| SCHEMBL9205477 | 0.77 | TSHR (0.49) | ALDH1A1ALOX15KDM4EHPGDGAA | |
| SCHEMBL9316182 | 0.75 | KDM4E (0.44) | ALDH1A1ALOX15KDM4EHPGDGAA | |
| SCHEMBL9315811 | 0.75 | ALOX15 (0.45) | ALDH1A1ALOX15KDM4EHPGDGAA | |
| SCHEMBL9316161 | 0.74 | KDM4E (0.43) | ALDH1A1ALOX15KDM4EHPGDGAA | |
| SCHEMBL8661697 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5959116-A | 5-NITRO PYRIDINE-2,3-DICARBOXYLIC ACID ESTER CHEMICAL INTERMEDIATES MADE BY REACTING THE N-OXIDES OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH NITRIC ACID OR SODIUM NITRATE, THEN REMOVING THE N-OXIDE GROUP | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | claimed |
| EP-0663399-B1 | Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants | BASF AG (DE) | 1998-06-10 | — | — | EP | claimed |
| US-5959116-A | 5-NITRO PYRIDINE-2,3-DICARBOXYLIC ACID ESTER CHEMICAL INTERMEDIATES MADE BY REACTING THE N-OXIDES OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH NITRIC ACID OR SODIUM NITRATE, THEN REMOVING THE N-OXIDE GROUP | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| US-5571774-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |