Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316161 | 0.87 | KDM4E (0.43) | KDM4ETSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9800425 | 0.80 | KDM4E (0.50) | KDM4ETSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8661094 | 0.77 | ALDH1A1 (0.50) | KDM4ETSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9315414 | 0.77 | SMN1; SMN2 (0.56) | KDM4ETSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8322828 | 0.77 | KDM4E (0.51) | KDM4ETSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL9205477 | 0.76 | TSHR (0.49) | KDM4ETSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8316014 | 0.75 | ALDH1A1 (0.57) | KDM4ETSHRALDH1A1ALOX15HPGD | |
| SCHEMBL9315811 | 0.73 | ALOX15 (0.45) | KDM4ETSHRALDH1A1ALOX15HSD17B10 | |
| SCHEMBL8323222 | 0.72 | ALDH1A1 (0.62) | KDM4ETSHRALDH1A1ALOX15HPGD | |
| SCHEMBL8661697 | 0.72 | ALDH1A1 (0.54) | KDM4ETSHRALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334576-A | Pre- and postemergence | AMERICAN CYANAMID COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| EP-0322616-A2 | Novel 5(and/or 6)substituted 2-(2-imidazolin-2-yl)nicotinic acids, esters and salts, useful as herbicidal agents and nivel intermediates for the preparation of said nicotinic acids, esters and salts | AMERICAN CYANAMID COMPANY (US) | 1989-07-05 | — | — | EP | disclosed |