Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS1 | P09382 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321037 | 0.91 | LGALS1 (0.35) | LGALS1NPSR1TSHRALDH1A1OPRK1 | |
| SCHEMBL9003394 | 0.88 | LGALS1 (0.36) | LGALS1NPSR1TSHRALDH1A1OPRK1 | |
| SCHEMBL7778659 | 0.84 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL7776037 | 0.83 | LGALS1 (0.46) | LGALS1NPSR1TSHRALDH1A1OPRK1 | |
| SCHEMBL8323458 | 0.78 | DNM1 (0.42) | LGALS1ALDH1A1DNM1MEN1KMT2A | |
| SCHEMBL8322672 | 0.78 | DNM1 (0.37) | LGALS1ALDH1A1DNM1MEN1KMT2A | |
| SCHEMBL7776039 | 0.77 | LGALS1 (0.46) | LGALS1NPSR1TSHRALDH1A1OPRK1 | |
| SCHEMBL9003285 | 0.76 | DNM1 (0.38) | LGALS1ALDH1A1DNM1MEN1KMT2A | |
| SCHEMBL7778645 | 0.75 | CYP1A2 (0.34) | TSHRALDH1A1CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL8323460 | 0.74 | NAAA (0.48) | LGALS1TSHRALDH1A1DNM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880130-A | TREATMENT OF CELL-PROLIFERATION DISEASES | ZENECA LIMITED (GB) | 1999-03-09 | — | — | US | disclosed |