Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20724252 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PKMACACBFDPSCYP3A4 | |
| SCHEMBL19765222 | 0.82 | CYP3A4 (0.46) | ALDH1A1PKMACACBFDPSCYP3A4 | |
| SCHEMBL6009308 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PKMACACBFDPSTSHR | |
| SCHEMBL30845136 | 0.81 | FDPS (0.42) | ALDH1A1PKMACACBFDPSCYP3A4 | |
| SCHEMBL3432947 | 0.81 | L3MBTL1 (0.47) | ALDH1A1PKMACACBFDPSCYP3A4 | |
| SCHEMBL4358364 | 0.81 | CYP3A4 (0.47) | ALDH1A1PKMCYP3A4L3MBTL1 | |
| SCHEMBL13264272 | 0.78 | CYP3A4 (0.48) | ALDH1A1PKMCYP3A4LMNAMAPT | |
| SCHEMBL13234062 | 0.77 | CYP3A4 (0.45) | ALDH1A1PKMCYP3A4L3MBTL1 | |
| SCHEMBL5543330 | 0.77 | L3MBTL1 (0.51) | ALDH1A1PKMCYP1A2CYP2C19FDPS | |
| SCHEMBL4759129 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1040983-A | Thieno-(3 ', 4 '-4,5) and imidazo (2,1-b) thiazole derivative, its preparation method and medicinal use | CHEM PHARM FORSCH GMBH (AT) | 1990-04-04 | — | — | CN | claimed |
| EP-0093376-B2 | 1-Sulfo-2-azetidinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| CN-1025197-C | Thiero[3',4'-4,5] imidazo[2,1-b] thiazol derivatives, process for preparing them and use as pharmaceutical | CHEM PHARM FORSCH GMBH (AT) | 1994-06-29 | — | — | CN | disclosed |
| CN-1040983-A | Thieno-(3 ', 4 '-4,5) and imidazo (2,1-b) thiazole derivative, its preparation method and medicinal use | CHEM PHARM FORSCH GMBH (AT) | 1990-04-04 | — | — | CN | disclosed |
| EP-0093376-B1 | 1-SULFO-2-AZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-21 | — | — | EP | disclosed |