Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317135 | 0.85 | CYP2D6 (0.43) | P2RX7MEN1MAPTKMT2AATM | |
| SCHEMBL7321555 | 0.81 | P2RX7 (0.52) | P2RX7MEN1MAPTKMT2A | |
| SCHEMBL21092222 | 0.81 | P2RX7 (0.52) | P2RX7MEN1MAPTKMT2A | |
| SCHEMBL8315667 | 0.76 | EPHX1 (0.41) | MEN1MAPTKMT2AEPHX1 | |
| SCHEMBL9290880 | 0.75 | SSTR4 (0.45) | MTNR1A | |
| SCHEMBL9379406 | 0.75 | MEN1 (0.46) | MEN1KMT2AEPHX1 | |
| SCHEMBL21091998 | 0.72 | NFKB1 (0.54) | — | |
| SCHEMBL21092001 | 0.72 | NFKB1 (0.54) | — | |
| SCHEMBL4197198 | 0.71 | CA2 (0.43) | — | |
| SCHEMBL7336911 | 0.71 | CA2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540914-B1 | 2-Aminomethylchromans as active ingredients in medicaments for the treatment of diseases of the central nervous system | BAYER AG (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0540914-A1 | 2-Aminomethylchromans as active ingredients in medicaments for the treatment of diseases of the central nervous system | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |