Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319517 | 0.85 | NFKB1 (0.52) | CYP2D6MAPTCYP2C19CYP1A2CYP3A4 | |
| SCHEMBL8317168 | 0.85 | P2RX7 (0.44) | MAPTP2RX7ATMMEN1KMT2A | |
| SCHEMBL8316604 | 0.78 | NFKB1 (0.55) | HCRTR1HCRTR2NFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL7319272 | 0.77 | NFKB1 (0.54) | HCRTR1HCRTR2NFKB1NFKB2RELA | |
| SCHEMBL9379902 | 0.76 | MTNR1A (0.45) | MAPTCYP1A2NFKB1NFKB2RELA | |
| SCHEMBL9040773 | 0.75 | MTNR1A (0.43) | MAPTCYP1A2CYP2C9 | |
| SCHEMBL9379681 | 0.73 | ALDH1A1 (0.46) | PKMHCRTR1HCRTR2HPGDMEN1 | |
| SCHEMBL7109070 | 0.73 | L3MBTL1 (0.45) | MAPTCYP1A2L3MBTL1MEN1KMT2A | |
| SCHEMBL7117287 | 0.73 | L3MBTL1 (0.45) | MAPTCYP1A2L3MBTL1MEN1KMT2A | |
| SCHEMBL6753107 | 0.72 | ATM (0.66) | CYP2D6MAPTCYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540914-B1 | 2-Aminomethylchromans as active ingredients in medicaments for the treatment of diseases of the central nervous system | BAYER AG (DE) | 1999-06-02 | — | — | EP | disclosed |
| EP-0540914-A1 | 2-Aminomethylchromans as active ingredients in medicaments for the treatment of diseases of the central nervous system | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |