Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319324 | 0.87 | RAB9A (0.64) | ALDH1A1LMNAPKMRAB9ACYP1A2 | |
| SCHEMBL7334998 | 0.86 | ALDH1A1 (0.65) | ALDH1A1LMNAPKMMAPTRAB9A | |
| SCHEMBL8318448 | 0.83 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNANPSR1MAPT | |
| SCHEMBL8317200 | 0.83 | RAB9A (0.54) | ALDH1A1LMNANPSR1PKMMAPT | |
| SCHEMBL6961250 | 0.82 | ALDH1A1 (0.54) | ALDH1A1TSHRLMNANPSR1PKM | |
| SCHEMBL8316866 | 0.82 | RAB9A (0.56) | ALDH1A1LMNANPSR1PKMMAPT | |
| SCHEMBL8315698 | 0.81 | RAB9A (0.53) | ALDH1A1LMNAPKMRAB9ACYP1A2 | |
| SCHEMBL7367123 | 0.81 | RAB9A (0.57) | ALDH1A1LMNANPSR1PKMMAPT | |
| SCHEMBL8315129 | 0.80 | WDR5 (0.52) | ALDH1A1LMNANPSR1PKMMAPT | |
| SCHEMBL8319629 | 0.80 | RAB9A (0.51) | ALDH1A1TSHRLMNAPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636625-B1 | Tricyclic diazepines vasopressin and oxytocin antagonists | AMERICAN CYANAMID CO (US) | 1999-01-27 | — | — | EP | disclosed |