Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709368 | 0.75 | MAPT (0.56) | MTNR1AMTNR1BPTPN1ALDH1A1MAPT | |
| SCHEMBL7706874 | 0.70 | ACHE (0.40) | ALDH1A1MAPTMEN1CYP1A2POLB | |
| SCHEMBL5723907 | 0.70 | MTNR1A (0.56) | MTNR1AMTNR1BPTPN1ALDH1A1 | |
| SCHEMBL14031174 | 0.66 | PTPN1 (0.61) | MTNR1AMTNR1BPTPN1CYP1A2 | |
| SCHEMBL23774243 | 0.65 | ACACB (0.71) | — | |
| SCHEMBL11857049 | 0.63 | MAPT (0.45) | MTNR1AMTNR1BPTPN1ALDH1A1MAPT | |
| SCHEMBL6171639 | 0.62 | ALDH1A1 (0.78) | ALDH1A1MEN1POLBKMT2A | |
| SCHEMBL1134101 | 0.61 | KMT2A (0.56) | MTNR1AMTNR1BALDH1A1MEN1KMT2A | |
| SCHEMBL7712137 | 0.61 | KMT2A (0.44) | ALDH1A1MAPTMEN1CYP1A2POLB | |
| SCHEMBL660541 | 0.61 | MMP13 (0.70) | MTNR1AMTNR1BALDH1A1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939754-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-08 | — | — | EP | claimed |
| WO-1998019648-A2 | N-OXY-NAPHTHALIMIDES AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-05-14 | — | — | WO | claimed |