Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317319 | 0.83 | KCNA5 (0.40) | CYP19A1KCNA5PDE4DFFAR1CFTR | |
| SCHEMBL9311705 | 0.82 | PDE4D (0.43) | PBRM1CYP19A1KCNA5PDE4DKCNH2 | |
| SCHEMBL9311940 | 0.81 | HRH1 (0.42) | CYP19A1KCNA5PDE4DFFAR1CFTR | |
| SCHEMBL128718 | 0.81 | CFTR (0.53) | CYP19A1KCNA5KCNH2CFTRSLC6A2 | |
| SCHEMBL9312935 | 0.80 | PDE4D (0.40) | KCNA5PDE4DFFAR1CFTRSLC6A2 | |
| SCHEMBL8313802 | 0.80 | FFAR1 (0.53) | KCNA5PDE4DFFAR1 | |
| SCHEMBL8319920 | 0.78 | PDE4D (0.48) | KCNA5PDE4DFFAR1 | |
| Ammonia Solution, Strong SCHEMBL8317322 | 0.78 | TBXAS1 (0.44) | CYP19A1KCNA5 | |
| SCHEMBL8318114 | 0.78 | SMN1; SMN2 (0.57) | KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9311485 | 0.77 | CYP19A1 (0.38) | CYP19A1KCNA5SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |