Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL6000029 | 0.83 | TBXAS1 (0.49) | TBXAS1CYP19A1CYP3A4CYP2C19KDM4E | |
| SCHEMBL8318114 | 0.83 | SMN1; SMN2 (0.57) | CYP3A4CYP2D6 | |
| SCHEMBL8317319 | 0.81 | KCNA5 (0.40) | TBXAS1CYP19A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6509102 | 0.80 | ADRB3 (0.38) | CYP19A1CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9311940 | 0.79 | HRH1 (0.42) | TBXAS1CYP19A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9312935 | 0.78 | PDE4D (0.40) | TBXAS1MAPTKCNA5 | |
| SCHEMBL8313802 | 0.78 | FFAR1 (0.53) | TBXAS1KCNA5 | |
| SCHEMBL8317214 | 0.78 | PBRM1 (0.42) | CYP19A1KCNA5 | |
| Ammonia Solution, Strong SCHEMBL5999497 | 0.76 | CFTR (0.61) | TBXAS1GRM2KDM4EKCNA5 | |
| SCHEMBL8319920 | 0.76 | PDE4D (0.48) | TBXAS1MAPTKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |