Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128718 | 0.85 | CFTR (0.53) | CYP19A1KCNA5KCNH2CFTRSLC6A2 | |
| SCHEMBL8317214 | 0.82 | PBRM1 (0.42) | PDE4DCYP19A1KCNA5KCNH2PBRM1 | |
| SCHEMBL9311629 | 0.79 | TBXAS1 (0.47) | PDE4DKCNA5KCNH2CFTRSLC6A2 | |
| SCHEMBL9313089 | 0.78 | PDE4D (0.45) | PDE4DKCNA5KCNH2CFTRSLC6A2 | |
| SCHEMBL6631615 | 0.77 | CFTR (0.52) | CYP19A1KCNA5CFTRSLC6A2SLC6A4 | |
| SCHEMBL9311555 | 0.73 | SMN1; SMN2 (0.66) | PDE4DCYP19A1CFTRSLC6A2SLC6A4 | |
| SCHEMBL12303932 | 0.72 | CYP19A1 (0.47) | CYP19A1KCNA5KCNH2CFTRSLC6A2 | |
| SCHEMBL9312096 | 0.72 | ALDH1A1 (0.41) | CYP19A1KCNA5KCNH2CFTRSLC6A2 | |
| SCHEMBL6344248 | 0.72 | CYP19A1 (0.50) | CYP19A1KCNA5KCNH2CFTRSLC6A2 | |
| SCHEMBL9312100 | 0.71 | KIF20A (0.48) | KCNH2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374641-A | Thromboxane synthetase inhibitors, prostaglandin H2 antagonist , anticoagulants and antiallergens | TERUMO KABUSHIKI KAISHA (JP) | 1994-12-20 | — | — | US | disclosed |
| EP-0501876-A1 | N-(3-pyridylalkyl)sulfonamide derivative and pharmaceutical preparation containing thereof | TERUMO KABUSHIKI KAISHA (JP) | 1992-09-02 | — | — | EP | disclosed |