Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9311940 | 0.90 | HRH1 (0.42) | KCNA5PDE4DCFTRSLC6A2SLC6A4 | |
| SCHEMBL8319920 | 0.84 | PDE4D (0.48) | KCNA5PDE4DFFAR1TBXAS1 | |
| SCHEMBL8317214 | 0.83 | PBRM1 (0.42) | KCNA5PDE4DCFTRSLC6A2SLC6A4 | |
| SCHEMBL8313802 | 0.83 | FFAR1 (0.53) | KCNA5PDE4DFFAR1TBXAS1 | |
| SCHEMBL9312935 | 0.83 | PDE4D (0.40) | KCNA5PDE4DCFTRSLC6A2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL8317322 | 0.81 | TBXAS1 (0.44) | KCNA5CHRNB2CHRNA4CYP3A4CYP2D6 | |
| SCHEMBL8318114 | 0.81 | SMN1; SMN2 (0.57) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL9311679 | 0.81 | ITGB3 (0.43) | KCNA5SLC6A2SLC6A4SLC6A3CYP3A4 | |
| SCHEMBL5307787 | 0.79 | HTR2A (0.64) | KCNA5HTR2ATAAR1AKT2AKT1 | |
| SCHEMBL4196224 | 0.79 | CFTR (0.57) | KCNA5HTR2ATAAR1AKT1CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |