Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313802 | 0.90 | FFAR1 (0.53) | PDE4DLMNAFFAR1TBXAS1HTT | |
| SCHEMBL8317319 | 0.84 | KCNA5 (0.40) | PDE4DFFAR1TBXAS1KCNA5 | |
| SCHEMBL17591689 | 0.82 | LMNA (0.54) | PDE4DLMNATBXAS1HTTHPGD | |
| SCHEMBL9311940 | 0.81 | HRH1 (0.42) | PDE4DFFAR1TBXAS1KCNA5KMT2A | |
| SCHEMBL9312935 | 0.81 | PDE4D (0.40) | PDE4DFFAR1TBXAS1KCNA5MAPT | |
| SCHEMBL8553222 | 0.79 | PDE4D (0.49) | PDE4DFFAR1RAB9A | |
| SCHEMBL8318114 | 0.78 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2GAA | |
| SCHEMBL8317214 | 0.78 | PBRM1 (0.42) | PDE4DFFAR1KCNA5 | |
| Ammonia Solution, Strong SCHEMBL8317322 | 0.76 | TBXAS1 (0.44) | TBXAS1KCNA5MAPT | |
| SCHEMBL6509102 | 0.75 | ADRB3 (0.38) | PDE4DLMNASMN1; SMN2KCNA5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0897920-A1 | NOVEL HETEROCYCLIC COMPOUNDS HAVING PLATELET AGGREGATION INHIBITORY EFFECTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1999-02-24 | — | — | EP | disclosed |