Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24335207 | 0.85 | KDM4E (0.45) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL11839637 | 0.84 | MAPT (0.48) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL8313816 | 0.82 | MAPT (0.43) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| Oxindole SCHEMBL9054033 | 0.80 | HTR7 (0.52) | AHRPDK2HTR7HTR1ADRD2 | |
| SCHEMBL1239067 | 0.80 | KMT2A (0.53) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL13729308 | 0.78 | KMT2A (0.64) | MEN1KMT2AMAPTEPHX2DRD2 | |
| SCHEMBL11551265 | 0.74 | BRPF1 (0.59) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL9049355 | 0.73 | HTR7 (0.63) | HTR7HTR1ADRD2DRD5DRD3 | |
| SCHEMBL5389753 | 0.71 | DRD2 (0.62) | DRD2DRD3 | |
| SCHEMBL4058329 | 0.70 | ALDH1A1 (0.56) | MEN1KMT2AHTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |