Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498908 | 0.85 | KMT2A (0.46) | ALDH1A1POLBCYP3A4CYP19A1CYP2C19 | |
| SCHEMBL1515880 | 0.84 | FFAR1 (0.40) | ALDH1A1POLBKMT2AL3MBTL1 | |
| SCHEMBL9312935 | 0.82 | PDE4D (0.40) | ADRB3ALDH1A1TP53POLBTDP1 | |
| SCHEMBL7492214 | 0.81 | MAPK1 (0.54) | KMT2A | |
| Ammonia Solution, Strong SCHEMBL8317322 | 0.80 | TBXAS1 (0.44) | CYP3A4CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL8318114 | 0.80 | SMN1; SMN2 (0.57) | ADRB3ADRB1ADRB2CYP3A4CYP2D6 | |
| SCHEMBL8317319 | 0.77 | KCNA5 (0.40) | PDE4DCYP3A4CYP2D6CYP19A1CYP2C9 | |
| SCHEMBL6987746 | 0.77 | TBXAS1 (0.37) | ADRB3CYP19A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL6505294 | 0.77 | ALDH1A1 (0.42) | ALDH1A1POLBCYP3A4CYP19A1LMNA | |
| SCHEMBL8313802 | 0.77 | FFAR1 (0.53) | PDE4DLMNASMN1; SMN2KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | ADRB3 2198/4885ALDH1A1 3345/4885TP53 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.