Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317675 | 0.87 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL8316701 | 0.80 | HCAR3 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL10533223 | 0.70 | NR1D1 (0.51) | ALDH1A1PKML3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL19928784 | 0.70 | HPGD (0.41) | ALDH1A1PKML3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL4993348 | 0.69 | PDGFRB (0.56) | ALDH1A1PKML3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL8264268 | 0.69 | S1PR4 (0.51) | ALDH1A1SMN1; SMN2MAPTKDM4EMAPK1 | |
| SCHEMBL741469 | 0.69 | MAPT (0.70) | ALDH1A1PKML3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL9272500 | 0.68 | ALDH1A1 (0.46) | ALDH1A1PKML3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL4659391 | 0.68 | MAPT (0.48) | ALDH1A1PKML3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL5102019 | 0.68 | NOS3 (0.49) | ALDH1A1PKML3MBTL1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536419-B1 | TRICYCLIC TRIAZOLE DERIVATIVES, PRODUCTION AND USE THEREOF | TORAY INDUSTRIES (JP) | 1999-10-13 | — | — | EP | disclosed |
| US-5683998-A | ANTIINFLAMMATORY AGENTS, ANTIALLERGENS, ANTIPAF AGENTS | TORAY INDUSTRIES, INC. (JP) | 1997-11-04 | — | — | US | disclosed |
| CN-1033327-C | Process for preparing tricyclotriazolo derivatives and their use | TORAY INDUSTRIES (JP) | 1996-11-20 | — | — | CN | disclosed |
| EP-0536419-A1 | TRICYCLIC TRIAZOLE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1993-04-14 | — | — | EP | disclosed |