SCHEMBL8317953

SCHEMBL8317953

CS(=O)(=O)OS(c1ccccc1)(c1ccc(OC2CCCCO2)cc1)c1ccc(OC2CCCCO2)cc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 3/20 0.36
THRB P10828 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPY2R P49146 1/20 0.35
TNK2 Q07912 2/20 0.35
HSD11B1 P28845 1/20 0.34
ENPP3 O14638 3/20 0.34
ENPP1 P22413 3/20 0.34
SLC9A3 P48764 1/20 0.34
ENPP2 Q13822 2/20 0.33
ACP1 P24666 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8323058 0.96 LMNA (0.40) LMNAMEN1KMT2AHTTALDH1A1
SCHEMBL8319160 0.90 HSD11B1 (0.41) LMNAMEN1KMT2AHTTALDH1A1
SCHEMBL8322121 0.87 DDB1 (0.34) MEN1KMT2ASMN1; SMN2TNK2HSD11B1
SCHEMBL8319790 0.86 DDB1 (0.39) LMNAMEN1KMT2AHTTALDH1A1
SCHEMBL25121933 0.84 TNK2 (0.38) LMNAMEN1KMT2AHTTALDH1A1
SCHEMBL8322273 0.83 GAA (0.36) LMNAKMT2AHTTALDH1A1SMN1; SMN2
SCHEMBL8649487 0.83 LMNA (0.34) LMNAMEN1KMT2AHTTALDH1A1
SCHEMBL8646303 0.83 MEN1 (0.36) LMNAMEN1KMT2AHTTALDH1A1
SCHEMBL8322235 0.82 HSD11B1 (0.37) MEN1KMT2AHTTALDH1A1SMN1; SMN2
SCHEMBL27344459 0.79 TNK2 (0.38) LMNAMEN1KMT2AHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5880169-A HAVING HIGH RESOLUTION FOR FINE PATTERNING SHIN-ETSU CHEMICAL CO., LTD. (JP) 1999-03-09 US disclosed