Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322121 | 0.97 | DDB1 (0.34) | GAAHPGDDDB1CRBNSMN1; SMN2 | |
| SCHEMBL8321361 | 0.89 | GAA (0.37) | GAAHPGDDDB1CRBNSMN1; SMN2 | |
| SCHEMBL8323058 | 0.87 | LMNA (0.40) | HPGDSMN1; SMN2NPC1KMT2ATP53 | |
| SCHEMBL8322235 | 0.86 | HSD11B1 (0.37) | GAADDB1CRBNSMN1; SMN2KMT2A | |
| SCHEMBL8650000 | 0.85 | GAA (0.35) | GAAHPGDDDB1CRBNSMN1; SMN2 | |
| SCHEMBL8317953 | 0.83 | LMNA (0.37) | SMN1; SMN2KMT2ALMNAALDH1A1HTT | |
| SCHEMBL8651827 | 0.82 | GAA (0.33) | GAAHPGDDDB1CRBNSMN1; SMN2 | |
| SCHEMBL8322269 | 0.81 | GAA (0.36) | GAAHPGDDDB1CRBNSMN1; SMN2 | |
| SCHEMBL8322119 | 0.78 | DDB1 (0.34) | GAAHPGDDDB1CRBNSMN1; SMN2 | |
| SCHEMBL6140612 | 0.77 | HPGD (0.37) | GAAHPGDSMN1; SMN2NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |