Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321361 | 0.97 | GAA (0.37) | HSD11B1DHFRGAADDB1CRBN | |
| SCHEMBL8322121 | 0.90 | DDB1 (0.34) | HSD11B1GAADDB1CRBNPOLB | |
| SCHEMBL8319160 | 0.90 | HSD11B1 (0.41) | HSD11B1DHFRDDB1CRBNALDH1A1 | |
| SCHEMBL8649669 | 0.87 | DHFR (0.35) | HSD11B1DHFRGAADDB1CRBN | |
| SCHEMBL8322273 | 0.86 | GAA (0.36) | GAADDB1CRBNALDH1A1HTT | |
| SCHEMBL8319790 | 0.86 | DDB1 (0.39) | HSD11B1DHFRDDB1CRBNALDH1A1 | |
| SCHEMBL8649675 | 0.84 | GAA (0.35) | HSD11B1DHFRGAADDB1CRBN | |
| SCHEMBL8317953 | 0.82 | LMNA (0.37) | HSD11B1ALDH1A1HTTSMN1; SMN2MEN1 | |
| SCHEMBL17120591 | 0.79 | DDB1 (0.49) | HSD11B1DHFRDDB1CRBNFAAH | |
| SCHEMBL8323058 | 0.78 | LMNA (0.40) | ALDH1A1POLBHTTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |