Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389839 | 0.92 | CCKBR (0.38) | KMT2ATGM2CCKBR | |
| SCHEMBL8313266 | 0.84 | FNTA (0.38) | CTSKMAPK1ITGB3ITGA2BCTSS | |
| SCHEMBL8311925 | 0.84 | CTSK (0.40) | CTSKMAPK1ITGB3ITGA2BCTSS | |
| SCHEMBL8316463 | 0.79 | MEN1 (0.42) | KMT2A | |
| SCHEMBL8312710 | 0.79 | FAAH (0.35) | CTSKMAPK1ITGB3ITGA2BKMT2A | |
| SCHEMBL8317004 | 0.76 | CTSK (0.42) | ADORA1CTSKMAPK1ITGB3ITGA2B | |
| SCHEMBL8316003 | 0.74 | CTSK (0.41) | ADORA1CTSKMAPK1ITGB3ITGA2B | |
| SCHEMBL8316006 | 0.74 | CTSK (0.41) | ADORA1CTSKMAPK1ITGB3ITGA2B | |
| SCHEMBL8314601 | 0.73 | ITGB3 (0.41) | ADORA1CTSKMAPK1ITGB3ITGA2B | |
| SCHEMBL8314603 | 0.73 | ITGB3 (0.41) | ADORA1CTSKMAPK1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662481-B1 | Spiro piperidines and homologs promote release of growth hormone | MERCK & CO INC (US) | 1999-03-24 | — | — | EP | disclosed |
| US-5578593-A | RELEASING GROWTH HORMONES FOR ANIMALS | MERCK & CO., INC. (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0662481-A1 | Spiro piperidines and homologs promote release of growth hormone | MERCK & CO. INC. (US) | 1995-07-12 | — | — | EP | disclosed |