Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533119 | 0.89 | MTTP (0.48) | LMNAALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL532902 | 0.88 | L3MBTL1 (0.43) | L3MBTL1LMNAALDH1A1NPSR1CHRNB2 | |
| SCHEMBL8320252 | 0.82 | ALDH1A1 (0.46) | L3MBTL1LMNAALDH1A1HTTCHRNB2 | |
| SCHEMBL532826 | 0.81 | ALDH1A1 (0.47) | L3MBTL1LMNAALDH1A1HTTNPSR1 | |
| SCHEMBL532809 | 0.81 | ALDH1A1 (0.46) | L3MBTL1LMNAALDH1A1HTTNPSR1 | |
| SCHEMBL5111860 | 0.80 | MTTP (0.40) | ALDH1A1NAMPTKMT2A | |
| SCHEMBL533307 | 0.80 | F10 (0.43) | L3MBTL1LMNAALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL533138 | 0.79 | NPC1 (0.46) | L3MBTL1LMNAALDH1A1CHRNB2CHRNB4 | |
| SCHEMBL532940 | 0.78 | GAA (0.50) | L3MBTL1LMNAALDH1A1HTTTAS1R3 | |
| SCHEMBL533536 | 0.78 | L3MBTL1 (0.49) | L3MBTL1LMNAALDH1A1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073634-A2 | PHENYLENEDIAMINE UROTENSIN-II RECEPTOR ANTAGONISTS AND CCR-9 ANTAGONISTS | ENCYSIVE PHARMACEUTICALS INC. (US) | 2004-09-02 | — | — | WO | disclosed |