Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.53 |
| ▸ | HTR2C | P28335 | 7/20 | 0.53 |
| ▸ | HTR7 | P34969 | 5/20 | 0.53 |
| ▸ | HTR6 | P50406 | 5/20 | 0.53 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8314934 | 0.82 | HTR2A (0.52) | HTR2AHTR2CHTR7HTR6DRD2 | |
| SCHEMBL6603889 | 0.80 | HTR2A (0.68) | HTR2AHTR2CHTR7HTR6GRM2 | |
| SCHEMBL8315456 | 0.77 | HTR2A (0.56) | HTR2AHTR2CHTR7HTR6DRD2 | |
| SCHEMBL9368018 | 0.75 | HTR2A (0.72) | HTR2AHTR2CHTR7HTR6GRM2 | |
| Hydrochloric Acid SCHEMBL9362999 | 0.74 | HTR2A (0.71) | HTR2AHTR2CHTR7HTR6GRM2 | |
| SCHEMBL9118626 | 0.74 | HTR2A (0.50) | HTR2AHTR2CHTR7HTR6GRM2 | |
| SCHEMBL10713583 | 0.72 | WNT3A (0.66) | HTR2AHTR2CHTR7HTR6GRM2 | |
| SCHEMBL11617490 | 0.72 | HTR2A (0.68) | HTR2AHTR2CHTR7HTR6DRD2 | |
| SCHEMBL8315452 | 0.72 | HTR2A (0.54) | HTR2AHTR2CHTR7HTR6CYP1A2 | |
| Hydrochloric Acid SCHEMBL11619993 | 0.71 | HTR2A (0.67) | HTR2AHTR2CHTR7HTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850235-B1 | QUINOLEIN-2(1H)-ONE DERIVATIVES AS SEROTONIN ANTAGONISTS | SANOFI SYNTHELABO (FR) | 1999-12-01 | — | — | EP | claimed |