SCHEMBL8319083

SCHEMBL8319083

C=C(OC(=C)c1ccc(Br)cc1)c1ccc(Br)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
CA1 P00915 3/20 0.42
CA2 P00918 3/20 0.42
CYP2A6 P11509 1/20 0.42
GSK3B P49841 3/20 0.39
ALOX15 P16050 1/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
OGG1 O15527 1/20 0.38
HDAC3 O15379 1/20 0.37
HDAC4 P56524 1/20 0.37
HDAC1 Q13547 1/20 0.37
HDAC7 Q8WUI4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3575516 0.80 MAPT (0.45) CES2CES1CA1CA2CYP2A6
SCHEMBL9300131 0.75 CES2 (0.43) CES2CES1CA1CA2CYP2A6
SCHEMBL5737596 0.75 ALDH1A1 (0.39) CES2CES1CA1CA2GSK3B
SCHEMBL6343638 0.75 MAPT (0.55) CES2CES1CA1CA2CYP2A6
SCHEMBL5049280 0.75 MAPT (0.55) CES2CES1CA1CA2CYP2A6
SCHEMBL21679933 0.75 CES2 (0.52) CES2CES1CA1CA2CYP2A6
SCHEMBL8321722 0.74 CES2 (0.46) CES2CES1CA1CA2CYP2A6
SCHEMBL10567241 0.74 CES2 (0.46) CES2CES1CA1CA2LMNA
SCHEMBL15514186 0.74 MASP2 (0.44) ALOX15LMNAMEN1MAPTMAPK1
SCHEMBL757521 0.74 ALDH1A1 (0.46) CES2CES1GSK3BLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985502-A TONERS WITH BINDER RESINS AND COLORS CANON KABUSHIKI KAISHA (JP) 1999-11-16 US disclosed