Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299362 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL10821105 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL6137641 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL9750672 | 0.86 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL10242354 | 0.85 | ALDH1A1 (0.72) | ALDH1A1HPGDMAPTNPC1KDM4E | |
| SCHEMBL244255 | 0.84 | ALDH1A1 (0.76) | ALDH1A1HPGDMAPTNPC1KDM4E | |
| SCHEMBL2309900 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTNPC1KDM4E | |
| SCHEMBL8507216 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL3454323 | 0.84 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTKDM4EMEN1 | |
| SCHEMBL9287012 | 0.84 | POLB (0.48) | ALDH1A1HPGDMAPTPOLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119751376-A | Preparation method of thifluzamide | 广东禾康精细化工有限公司 | 2025-04-04 | — | — | CN | disclosed |
| CN-116354902-A | Green and environment-friendly process for synthesizing 2-methyl-4-trifluoromethyl-5-thiazole formic acid | 广东禾康精细化工有限公司 | 2023-06-30 | — | — | CN | disclosed |
| EP-3186227-B1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | ELANCO TIERGESUNDHEIT AG (CH) | 2021-03-24 | — | — | EP | disclosed |
| EP-3792251-A1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | Elanco Tiergesundheit AG (CH) | 2021-03-17 | — | — | EP | disclosed |
| US-10464889-B2 | Sulfonylaminobenzamide compounds as anthelmintics | ELANCO TIERGESUNDHEIT AG (US) | 2019-11-05 | — | — | US | disclosed |
| US-20180161331-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2018-06-14 | — | — | US | disclosed |
| US-9889136-B2 | Tetrahydropyridopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| US-20170226053-A1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | NOVARTIS TIERGESUNDHEIT AG (CH) | 2017-08-10 | — | — | US | disclosed |
| US-20170226053-A1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | NOVARTIS TIERGESUNDHEIT AG (CH) | 2017-08-10 | — | — | US | disclosed |
| US-9662333-B2 | Tetrahydropyridopyrimidine compound or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2017-05-30 | — | — | US | disclosed |
| EP-0648742-A1 | Improved process for the preparation of thioacetamide | ROHM AND HAAS COMPANY (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0371950-B1 | Substituted thiazoles and their use as fungicides | MONSANTO CO (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5284974-A | Reaction of acetonitrile with hydrogen sulfide using a polymer supported amine catalyst | MONSANTO COMPANY (US) | 1994-02-08 | — | — | US | disclosed |
| CN-1021010-C | SUBSTITUTED THIAZOLES COMPOSITION AND THEIR USE AS FUNGICIDES | MONSANTO CO (US) | 1993-06-02 | — | — | CN | disclosed |
| EP-0276177-B1 | HETEROCYCLIC DERIVATIVES, METHOD FOR THEIR PREPARATION AND FUNGICIDES CONTAINING THEM AS ACTIVE INGREDIENTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-01-29 | — | — | EP | disclosed |
| US-5045554-A | Fluoro compounds, rice sheath blight, Basidiomycetes type fungus | MONSANTO COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| CN-1043127-A | Substituted thiazole and mycocide purposes thereof | MONSANTO CO (US) | 1990-06-20 | — | — | CN | disclosed |
| EP-0371950-A2 | Substituted thiazoles and their use as fungicides | Monsanto Company (US) | 1990-06-06 | — | — | EP | disclosed |
| US-4837242-A | Thiazoles and pyrazoles as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-06 | — | — | US | disclosed |
| EP-0276177-A1 | Heterocyclic derivatives, method for their preparation and fungicides containing them as active ingredients | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161331-A1 | NOVEL TETRAHYDROPYRIDOPYRIMIDINE COMPOUND OR SALT THEREOF | NR5A1, CYP17A1, AR | ALDH1A1 295/4885HPGD 208/4885MAPT 2428/4885 |
| US-20170226053-A1 | NOVEL SULFONYLAMINOBENZAMIDE COMPOUNDS AS ANTHELMINTICS | PKD2, CATSPER1, PKD1 | ALDH1A1 1365/4885HPGD 3420/4885MAPT 4755/4885 |
| US-10464889-B2 | Sulfonylaminobenzamide compounds as anthelmintics | PKD2, CATSPER1, ATP1B2 | ALDH1A1 1120/4885HPGD 2857/4885MAPT 4705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.