Sugi Predict

Sugi Predict / Compounds / SCHEMBL244255

SCHEMBL244255

SCHEMBL244255

CCOC(=O)c1sc(N)nc1C(F)(F)F

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.76
▸ HPGD P15428 4/20 0.76
▸ CYP1A2 P05177 1/20 0.63
▸ HSD17B10 Q99714 2/20 0.53
▸ KDM4E B2RXH2 4/20 0.51
▸ LMNA P02545 1/20 0.48
▸ MAPT P10636 6/20 0.46
▸ MEN1 O00255 4/20 0.46
▸ KMT2A Q03164 4/20 0.46
▸ HSP90AA1 P07900 1/20 0.46
▸ CRHBP P24387 1/20 0.46
▸ CRHR2 Q13324 1/20 0.46
▸ FBP1 P09467 1/20 0.45
▸ NPC1 O15118 2/20 0.45
▸ RAB9A P51151 2/20 0.45
▸ IDO1 P14902 1/20 0.44
▸ GAA P10253 2/20 0.44
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ CDC7 O00311 1/20 0.43
▸ DBF4 Q9UBU7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL882389 0.88 ALDH1A1 (0.72) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL289519 0.86 ALDH1A1 (1.00) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL2145779 0.84 ALDH1A1 (0.54) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL10821105 0.83 ALDH1A1 (0.52) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL6137641 0.83 ALDH1A1 (0.52) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL299362 0.83 ALDH1A1 (0.52) ALDH1A1HPGDCYP1A2KDM4ELMNA
SCHEMBL9750672 0.83 ALDH1A1 (0.52) ALDH1A1HPGDCYP1A2KDM4ELMNA
SCHEMBL16166464 0.82 ALDH1A1 (0.52) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL11162259 0.82 ALDH1A1 (0.52) ALDH1A1HPGDCYP1A2HSD17B10KDM4E
SCHEMBL8507216 0.82 ALDH1A1 (0.51) ALDH1A1HPGDCYP1A2HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346626-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE INVOX PHARMA LTD (GB) 2025-11-13 — — US disclosed
US-12390668-B2 Compounds, compositions, and methods for the treatment of disease INVOX PHARMA LIMITED (GB) 2025-08-19 — — US disclosed
CN-119874654-A Pyran compound as plant immune activator and application thereof 华东理工大学 2025-04-25 — — CN disclosed
US-20250084074-A1 SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS MERCK PATENT GMBH (DE) 2025-03-13 — — US disclosed
US-12187761-B2 Compounds, compositions, and methods for the treatment of disease INVOX PHARMA LIMITED (GB) 2025-01-07 — — US disclosed
EP-4463444-A1 SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS Merck Patent GmbH (DE) 2024-11-20 — — EP disclosed
US-20240208961-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. 2024-06-27 — — US disclosed
US-20240208961-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. 2024-06-27 — — US disclosed
WO-2024102455-A1 NON-COVALENT INHIBITORS OF CORONAVIRUS MAIN PROTEASE EMORY UNIVERSITY (US) 2024-05-16 — — WO disclosed
US-20240058461-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE INVOX PHARMA LIMITED (GB) 2024-02-22 — — US disclosed
WO-2002000649-A1 SUBSTITUTED QUINAZOLINE DERIVATIVES AND THEIR USE AS INHIBITORS ASTRAZENECA AB (SE) 2002-01-03 — — WO disclosed
WO-2001058853-A1 DEHYDROAMINO ACIDS F. HOFFMANN-LA ROCHE AG (CH) 2001-08-16 — — WO disclosed
WO-2000062778-A1 CYCLIC PROTEIN TYROSINE KINASE INHIBITORS BRISTOL-MYERS SQUIBB CO. (US) 2000-10-26 — — WO disclosed
WO-1991001311-A1 SUBSTITUTED CARBOXANILIDOTHIAZOLES AND THEIR USE AS FUNGICIDES MONSANTO COMPANY (US) 1991-02-07 — — WO disclosed
US-4602937-A PLANT SAFENING AGENTS, ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1986-07-29 — — US disclosed
US-4602454-A PLANT SAFENING AGENTS, SEEDS CHLOROACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1986-07-29 — — US disclosed
US-4586948-A 2,4-disubstituted-5-thiazole-carboxylic acids and derivatives MONSANTO COMPANY (US) 1986-05-06 — — US disclosed
US-4437876-A PLANT SAFENING AGENTS FOR ACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1984-03-20 — — US disclosed
US-4437875-A PLANT SAFENING AGENT FOR ACETAMIDE HERBICIDE MONSANTO COMPANY (US) 1984-03-20 — — US disclosed
US-4199506-A REDUCES HERBICIDAL INJURY TO PLATNS DUE TO ACETAMIDE HERBICIDES MONSANTO COMPANY (US) 1980-04-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084074-A1 SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS VHL, CDKN1A, CCNI ALDH1A1 1680/4885HPGD 204/4885CYP1A2 2245/4885
US-20240208961-A1 EIF4E INHIBITORS AND USES THEREOF EIF4E, EIF4EBP1, EIF4A1 ALDH1A1 4776/4885HPGD 4535/4885CYP1A2 4834/4885
US-20240058461-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE STING1, MAVS, IRF3 ALDH1A1 3301/4885HPGD 2344/4885CYP1A2 4560/4885
US-20250346626-A1 COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE STING1, MAVS, IRF3 ALDH1A1 3301/4885HPGD 2344/4885CYP1A2 4560/4885
US-12390668-B2 Compounds, compositions, and methods for the treatment of disease STING1, MAVS, IRF3 ALDH1A1 3301/4885HPGD 2344/4885CYP1A2 4560/4885
US-12187761-B2 Compounds, compositions, and methods for the treatment of disease STING1, MAVS, IRF3 ALDH1A1 3301/4885HPGD 2344/4885CYP1A2 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.