Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.41 |
| ▸ | TNF | P01375 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAT2A | P31153 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317211 | 0.84 | NQO2 (0.48) | NQO2KDM4EALDH1A1SMN1; SMN2PDGFRB | |
| SCHEMBL12068383 | 0.81 | KDM4E (0.50) | NQO2KDM4EALDH1A1SMN1; SMN2AMY1A | |
| SCHEMBL8324287 | 0.80 | NQO2 (0.58) | NQO2KDM4EALDH1A1SMN1; SMN2PDGFRB | |
| SCHEMBL1428347 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1AMY1ATSHRMAPK1 | |
| SCHEMBL12074846 | 0.72 | NQO2 (0.40) | NQO2KDM4EALDH1A1SMN1; SMN2PDGFRB | |
| SCHEMBL14906874 | 0.71 | NQO2 (0.39) | NQO2KDM4EALDH1A1TSHRCASP1 | |
| SCHEMBL8318316 | 0.71 | TLR8 (0.54) | NQO2KDM4EALDH1A1SMN1; SMN2PDGFRB | |
| SCHEMBL9755422 | 0.71 | NQO2 (0.60) | NQO2KDM4EALDH1A1SMN1; SMN2PDGFRB | |
| SCHEMBL8498365 | 0.70 | TDP1 (0.44) | KDM4EALDH1A1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL14906876 | 0.70 | MAOA (0.38) | NQO2KDM4EALDH1A1SMN1; SMN2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981541-A | ACRIDINE DERIVATIVES; ANTICANCER AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-11-09 | — | — | US | claimed |
| US-5981541-A | ACRIDINE DERIVATIVES; ANTICANCER AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-11-09 | — | — | US | disclosed |
| EP-0950054-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-TUMOR AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1999-10-20 | — | — | EP | disclosed |
| WO-1998012181-A1 | SUBSTITUTED HETEROCYCLES AS ANTI-TUMOR AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-03-26 | — | — | WO | disclosed |