Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 5/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459513 | 0.78 | AR (0.36) | AR | |
| SCHEMBL7636053 | 0.73 | PGR (0.35) | PGRSLC22A12RORC | |
| SCHEMBL7632414 | 0.67 | GAA (0.35) | ARKDM4EGAA | |
| SCHEMBL7628632 | 0.57 | MTNR1A (0.38) | PGR | |
| SCHEMBL11697440 | 0.57 | SMN1; SMN2 (0.37) | KDM4EGAA | |
| SCHEMBL2473598 | 0.56 | SLC22A12 (0.41) | PGRARSLC22A12 | |
| SCHEMBL10979117 | 0.55 | MAPT (0.47) | KDM4EGAA | |
| SCHEMBL145418 | 0.55 | TRPV4 (0.54) | ARSLC22A12 | |
| SCHEMBL23792337 | 0.54 | PGR (0.38) | PGRKDM4E | |
| SCHEMBL8069814 | 0.54 | KDM4E (0.37) | ARKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888327-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034885-A1 | BENZOPYRAN DERIVATIVES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION | LABORATORIOS MENARINI S.A. (ES) | 1997-09-25 | — | — | WO | disclosed |