Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319163 | 0.99 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL8323847 | 0.85 | TSHR (0.37) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL8324231 | 0.85 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL8325988 | 0.82 | PDE4D (0.35) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL8325518 | 0.82 | MAPT (0.38) | ALDH1A1MAPTKDM4EHPGDTSHR | |
| SCHEMBL8324502 | 0.81 | PDE4A (0.33) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8324499 | 0.79 | CNR2 (0.35) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8318940 | 0.78 | PDE4A (0.58) | ALDH1A1MAPTKDM4EKMT2AMEN1 | |
| SCHEMBL8319816 | 0.78 | PDE4D (0.63) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8324668 | 0.77 | PDE4A (0.59) | ALDH1A1MAPTKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |