Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323847 | 0.88 | TSHR (0.37) | TSHRMEN1MAPTKMT2AMAPK1 | |
| SCHEMBL8319163 | 0.83 | ALDH1A1 (0.39) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL8320953 | 0.82 | ALDH1A1 (0.39) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL8324502 | 0.81 | PDE4A (0.33) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8324231 | 0.80 | ALDH1A1 (0.43) | MEN1MAPTHTTKMT2AMAPK1 | |
| SCHEMBL8324421 | 0.79 | PDE4D (0.44) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL8324499 | 0.77 | CNR2 (0.35) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL8325539 | 0.76 | ALDH1A1 (0.50) | PDE4DPDE4APDE4BPDE4CTSHR | |
| SCHEMBL5809786 | 0.69 | PDE4D (0.51) | PDE4DPDE4APDE4BPDE4CMEN1 | |
| SCHEMBL6921360 | 0.68 | ALDH1A1 (0.43) | TSHRMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069831-A1 | TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS LTD. (US) | 2004-08-19 | — | — | WO | disclosed |