SCHEMBL832150

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL831142	0.97	TP53 (0.53)	TP53LMNAMEN1KMT2AL3MBTL1
	SCHEMBL832059	0.90	TP53 (0.61)	TP53LMNAMEN1KMT2AL3MBTL1
	SCHEMBL830838	0.89	NPC1 (0.59)	TP53LMNAMEN1KMT2APOLB
	SCHEMBL830197	0.83	MEN1 (0.56)	MEN1KMT2AL3MBTL1POLBHPGD
	SCHEMBL831304	0.83	MAPT (0.59)	LMNAMEN1KMT2AL3MBTL1POLB
	SCHEMBL10800748	0.82	NPC1 (0.61)	TP53LMNAMEN1KMT2AL3MBTL1
	SCHEMBL2354864	0.82	RAB9A (0.57)	LMNAMEN1KMT2AL3MBTL1HPGD
	SCHEMBL4264046	0.82	PTGS2 (0.58)	LMNAMEN1KMT2AL3MBTL1POLB
	SCHEMBL13935133	0.82	PTGS2 (0.58)	LMNAMEN1KMT2AL3MBTL1POLB
	SCHEMBL830549	0.82	LMNA (0.52)	TP53LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.