Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21955999 | 1.00 | HCAR2 (0.45) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL25405174 | 0.97 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL16505 | 0.97 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL25405178 | 0.97 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL16504 | 0.97 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL16503 | 0.97 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| SCHEMBL8952295 | 0.89 | NFE2L2 (0.65) | HCAR2KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9514096 | 0.89 | HCAR2 (0.54) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| Crotonic Acid SCHEMBL7250369 | 0.86 | HCAR2 (0.44) | HCAR2KEAP1NFE2L2ALDH1A1TSHR | |
| Crotonic Acid SCHEMBL8811577 | 0.86 | HCAR2 (0.44) | HCAR2KEAP1NFE2L2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4057525-A | MELAMINE RESIN, ACRYLIC RESIN | KOWA CHEMICAL INDUSTRY LTD. (JA) | 1977-11-08 | — | — | US | claimed |
| US-8143176-B2 | Textile two or three dimensional fabric containing materials that are capable of swelling | BASF AKTIENGESELLSCHAFT (DE) | 2012-03-27 | — | — | US | disclosed |
| US-20100041291-A1 | TEXTILE TWO OR THREE DIMENSIONAL FABRIC CONTAINING MATERIALS THAT ARE CAPABLE OF SWELLING | BASF AKTIENGESELLSCHAFT (DE) | 2010-02-18 | — | — | US | disclosed |
| US-7652111-B2 | (Meth)acrylic acid esters of unsaturated aminoalcohols and preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 2010-01-26 | — | — | US | disclosed |
| US-20070043191-A1 | (Meth)acrylic acid esters of unsaturated aminoalcohols and preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 2007-02-22 | — | — | US | disclosed |
| EP-0321088-B1 | Process for preparing dispersions of advanced epoxy resins | ICI PLC (GB) | 1994-01-26 | — | — | EP | disclosed |
| US-4952456-A | Epoxide advancement | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-28 | — | — | US | disclosed |
| EP-0321088-A2 | Process for preparing dispersions of advanced epoxy resins | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043191-A1 | (Meth)acrylic acid esters of unsaturated aminoalcohols and preparation thereof | ALAD, ADH1A, PAM | HCAR2 185/4885KEAP1 1957/4885NFE2L2 3636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.