Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3986140 | 0.80 | ALDH1A1 (0.54) | SIGMAR1ALDH1A1NPC1ALOX15RAB9A | |
| SCHEMBL3905278 | 0.77 | MAPK1 (0.49) | LMNATHRBSIGMAR1ALDH1A1MAPT | |
| SCHEMBL155267 | 0.77 | QDPR (0.68) | LMNATHRB | |
| SCHEMBL5546722 | 0.77 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1MAPTMAPK1HPGD | |
| SCHEMBL5544864 | 0.76 | L3MBTL1 (0.39) | ALDH1A1 | |
| SCHEMBL4674057 | 0.76 | ALDH1A1 (0.49) | LMNATHRBSIGMAR1ALDH1A1MAPT | |
| SCHEMBL8010714 | 0.73 | SIGMAR1 (0.72) | SIGMAR1MAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL15449630 | 0.73 | MEN1 (0.51) | LMNATHRBSIGMAR1ALDH1A1MAPT | |
| SCHEMBL7910148 | 0.73 | NPSR1 (0.60) | LMNATHRBSIGMAR1MAPK1ALOX15 | |
| SCHEMBL7978448 | 0.73 | SIGMAR1 (0.61) | SIGMAR1MAPK1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945421-A | TREATING PSYCHOSIS AND SCHIZOPHRENIA | WARNER-LAMBERT COMPANY (US) | 1999-08-31 | — | — | US | disclosed |