Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.50 |
| ▸ | UBE2M | P61081 | 1/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23699903 | 0.78 | ALDH1A1 (0.71) | GAAALDH1A1UBE2MDCUN1D1KDM4E | |
| SCHEMBL9001748 | 0.77 | TSHR (0.68) | ALDH1A1L3MBTL1MAPTSMN1; SMN2SLC6A9 | |
| SCHEMBL13911220 | 0.75 | SMN1; SMN2 (0.50) | NPC1CYP2C19CYP1A2CYP3A4GAA | |
| SCHEMBL16599594 | 0.75 | ABCC1 (0.54) | NPC1RAB9ACYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL1685099 | 0.73 | CCR5 (0.57) | NPC1RAB9AALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL27266162 | 0.73 | PPARG (0.57) | NPC1RAB9ACYP2C19CYP1A2CYP3A4 | |
| SCHEMBL13900756 | 0.72 | SMN1; SMN2 (0.49) | L3MBTL1SMN1; SMN2ABCC1TSHRLMNA | |
| SCHEMBL10720319 | 0.71 | L3MBTL1 (0.60) | CYP2C19CYP1A2CYP3A4GAAALDH1A1 | |
| SCHEMBL9262963 | 0.71 | RAB9A (0.60) | NPC1RAB9ACYP2C19CYP1A2ALDH1A1 | |
| SCHEMBL9261671 | 0.71 | UBE2M (0.59) | NPC1RAB9ACYP2C19ALDH1A1UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1060475-C | Process for preparing 1-aryl-4-carbamoyl-tetrazolinones | BAYER AG (DE) | 2001-01-10 | — | — | CN | disclosed |
| US-5877323-A | Process for preparing 1-aryl-4-carbamoyl-tetrazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-02 | — | — | US | disclosed |
| US-5874586-A | Process for preparing 1-aryl-4-carbamoyl-tetrazolinones | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-23 | — | — | US | disclosed |
| CN-1153777-A | Process for preparing 1-aryl-4-carbamoyl-tetrazolinones | BAYER AG (DE) | 1997-07-09 | — | — | CN | disclosed |