Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | KIF18A | Q8NI77 | 7/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | CENPE | Q02224 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22120881 | 0.83 | NSD2 (0.49) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL8112810 | 0.81 | SLC40A1 (0.49) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL2996719 | 0.79 | MAPT (0.45) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL9378913 | 0.79 | KIF18A (0.47) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL16007096 | 0.76 | ALDH1A1 (0.44) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL845336 | 0.74 | CYP3A4 (0.43) | SMN1; SMN2ALDH1A1CYP3A4TSHRNFE2L2 | |
| SCHEMBL20303167 | 0.72 | ALDH1A1 (0.41) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL9866733 | 0.72 | MAPT (0.39) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL8688550 | 0.71 | L3MBTL1 (0.56) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL989588 | 0.71 | CYP3A4 (0.50) | MAPTHPGDALDH1A1CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869428-A | CONTROLLING WEEDS | ISHIHARA SANGYO KAISHA LTD. (JP) | 1999-02-09 | — | — | US | disclosed |
| EP-0733629-A1 | Pyridonesulfonylurea compounds, process for their production and herbicides containing them | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |