Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | KIF18A | Q8NI77 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PARG | Q86W56 | 1/20 | 0.33 |
| ▸ | CENPE | Q02224 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866318 | 0.77 | ALDH1A1 (0.36) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8112810 | 0.73 | SLC40A1 (0.49) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL2996719 | 0.72 | MAPT (0.45) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL9378913 | 0.72 | KIF18A (0.47) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL8322949 | 0.72 | MAPT (0.45) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL22120881 | 0.72 | NSD2 (0.49) | MAPTSMN1; SMN2KDM4EMEN1NPC1 | |
| SCHEMBL9865417 | 0.70 | SMN1; SMN2 (0.37) | SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9868471 | 0.70 | CA12 (0.34) | SMN1; SMN2LMNAALDH1A1CA12CA1 | |
| SCHEMBL9867057 | 0.68 | ALDH1A1 (0.35) | SMN1; SMN2KDM4EMEN1LMNAKMT2A | |
| SCHEMBL9867680 | 0.67 | NFE2L2 (0.34) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |
| EP-0356029-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-28 | — | — | EP | disclosed |