Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 6/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.40 |
| ▸ | GABRP | O00591 | 4/20 | 0.40 |
| ▸ | GABRD | O14764 | 4/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.40 |
| ▸ | GABRE | P78334 | 4/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324003 | 0.86 | CDC7 (0.36) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8323244 | 0.83 | RECQL (0.36) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8322859 | 0.78 | RORC (0.39) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8320585 | 0.68 | CDC7 (0.39) | KDM4EMAPTALDH1A1L3MBTL1CDC7 | |
| SCHEMBL8324428 | 0.68 | RECQL (0.51) | LMNACYP3A4SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2827266 | 0.66 | BIRC5 (0.50) | GABRA2GABRB2GABRB3GABRPGABRD | |
| SCHEMBL8671264 | 0.66 | MAPT (0.58) | LMNASMN1; SMN2KDM4EMAPTALDH1A1 | |
| SCHEMBL8666855 | 0.66 | TDP1 (0.44) | LMNACYP3A4SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8319454 | 0.64 | MAT2A (0.42) | CYP3A4KDM4EMAPTALDH1A1GAA | |
| SCHEMBL2545891 | 0.64 | GABRA2 (0.44) | GABRA2GABRB2GABRB3GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0729470-B1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | claimed |
| WO-1995014019-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-05-26 | — | — | WO | claimed |
| EP-0729470-B1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LTD (GB) | 1999-05-12 | — | — | EP | disclosed |
| US-5451566-A | PREEMERGENCE AND POSTEMERGENCE HERBICIDES | ZENECA LIMITED (GB) | 1995-09-19 | — | — | US | disclosed |
| WO-1995014019-A1 | HERBICIDAL PYRROLOPYRIDINE COMPOUNDS | ZENECA LIMITED (GB) | 1995-05-26 | — | — | WO | disclosed |