Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.35 |
| ▸ | CTSB | P07858 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8622262 | 0.78 | ALDH1A1 (0.36) | CTSSCTSBCTSLALDH1A1PKM | |
| SCHEMBL8323557 | 0.78 | LMNA (0.35) | CTSSCTSBCTSLALDH1A1PKM | |
| SCHEMBL8326703 | 0.78 | PLA2G1B (0.38) | CTSSCTSBCTSLALDH1A1PKM | |
| SCHEMBL13995922 | 0.77 | TACR1 (0.41) | ALDH1A1PKMMEN1KMT2ATACR1 | |
| SCHEMBL8327295 | 0.75 | IDO1 (0.40) | ALDH1A1MEN1KMT2ATACR1BCHE | |
| SCHEMBL8329466 | 0.71 | NRP1 (0.33) | CTSSCTSBCTSLALDH1A1MEN1 | |
| SCHEMBL172705 | 0.71 | TACR1 (0.46) | TACR1BCHE | |
| SCHEMBL13995917 | 0.68 | TACR1 (0.46) | CTSSCTSLKMT2ATACR1BCHE | |
| SCHEMBL25591014 | 0.67 | TAAR1 (0.41) | ALDH1A1PKMKMT2ALMNA | |
| SCHEMBL14422854 | 0.66 | TSHR (0.54) | KMT2ATACR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |