Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NRP1 | O14786 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CASR | P41180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322051 | 0.78 | ALDH1A1 (0.42) | LRRK2CTSLGRM1KDM4EALDH1A1 | |
| SCHEMBL8330575 | 0.77 | MEN1 (0.35) | KDM4EALDH1A1TP53GAAMAPK1 | |
| SCHEMBL8324185 | 0.76 | CHRM2 (0.39) | KDM4EALDH1A1TP53GAAMAPK1 | |
| SCHEMBL8328869 | 0.76 | CHRM2 (0.44) | KDM4EALDH1A1TP53GAAL3MBTL1 | |
| SCHEMBL8329010 | 0.76 | CHRM2 (0.41) | CTSLKDM4EALDH1A1TP53GAA | |
| SCHEMBL8325662 | 0.75 | CHRM2 (0.46) | KDM4EALDH1A1TP53GAAL3MBTL1 | |
| SCHEMBL8326703 | 0.71 | PLA2G1B (0.38) | CTSLCTSBCTSSALDH1A1TSHR | |
| SCHEMBL8323561 | 0.71 | CTSS (0.35) | CTSLCTSBCTSSALDH1A1L3MBTL1 | |
| SCHEMBL13995922 | 0.70 | TACR1 (0.41) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8323557 | 0.70 | LMNA (0.35) | CTSLCTSBCTSSKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5736550-A | TREATMENT OF GASTROINTESTINAL TRACT DISORDERS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |