Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.35 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | GOT1 | P17174 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318119 | 0.84 | RARB (0.44) | WDR5FABP4FABP5HIF1AKMT2A | |
| SCHEMBL8766838 | 0.77 | MEN1 (0.35) | FABP4FABP5KMT2AMEN1NR1I2 | |
| SCHEMBL21194961 | 0.73 | GPR35 (0.43) | HIF1AEPAS1SERPINE1KMT2AMEN1 | |
| SCHEMBL4747624 | 0.72 | RARB (0.61) | WDR5KMT2AMEN1NR1I2LMNA | |
| SCHEMBL8323848 | 0.71 | KMT2A (0.50) | HIF1AEPAS1KMT2AMEN1KDM4E | |
| SCHEMBL29560409 | 0.70 | MAPT (0.49) | WDR5KMT2AMEN1TDP1 | |
| SCHEMBL635407 | 0.70 | MAPT (0.49) | WDR5KMT2AMEN1TDP1 | |
| SCHEMBL9317943 | 0.69 | WDR5 (0.51) | WDR5HIF1AKMT2AMEN1NR1I2 | |
| SCHEMBL29222875 | 0.69 | WDR5 (0.45) | WDR5KMT2AMEN1NR1I2LMNA | |
| SCHEMBL8322288 | 0.69 | RARB (0.49) | WDR5KMT2AMEN1NR1I2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0584191-B1 | NOVEL AROMATIC AND POLYCYCLIC COMPOUNDS AND THEIR USE IN HUMAN OR VETERINARY MEDICINE AND IN COSMETICS | CIRD GALDERMA (FR) | 1997-08-13 | — | — | EP | disclosed |