Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8647659 | 0.86 | CXCR4 (0.35) | TP53TSHRKDM4EMEN1KMT2A | |
| SCHEMBL8081813 | 0.86 | MEN1 (0.40) | DHFRHSD11B1TSHRMEN1KMT2A | |
| SCHEMBL8645325 | 0.85 | S1PR3 (0.34) | TP53DHFRHSD11B1TSHRMEN1 | |
| SCHEMBL8647852 | 0.85 | DHFR (0.38) | TP53DHFRHSD11B1MEN1KMT2A | |
| SCHEMBL8324624 | 0.84 | DHFR (0.43) | TP53DHFRHSD11B1TSHRCTSD | |
| SCHEMBL8319788 | 0.84 | LMNA (0.36) | TP53DHFRHSD11B1TSHRMEN1 | |
| SCHEMBL8649686 | 0.83 | TSHR (0.38) | TP53DHFRHSD11B1TSHRMEN1 | |
| SCHEMBL8081808 | 0.83 | MEN1 (0.38) | DHFRHSD11B1MEN1KMT2ALMNA | |
| SCHEMBL8078886 | 0.83 | MEN1 (0.38) | DHFRHSD11B1MEN1KMT2ALMNA | |
| SCHEMBL8645082 | 0.82 | DHFR (0.36) | TP53DHFRHSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824824-A | AROMATIC SULFONATE ANIONS AND DISSOLUTION CONTRAST IN EXPOSED AND NONEXPOSED AREAS, POSITIVE RESISTS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |