Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328374 | 0.85 | ACHE (0.42) | ACHE | |
| SCHEMBL8327173 | 0.84 | PRKAA2 (0.42) | SIGMAR1ALDH1A1ACHE | |
| SCHEMBL8327922 | 0.82 | BCHE (0.35) | MAPTMITFALDH1A1HTTRAB9A | |
| SCHEMBL8326437 | 0.82 | KDM4E (0.43) | MAPTHTTMAPK1GAAACHE | |
| SCHEMBL8322051 | 0.81 | ALDH1A1 (0.42) | MAPTMITFALDH1A1HTTRAB9A | |
| SCHEMBL8328418 | 0.81 | POLB (0.44) | ALDH1A1GAA | |
| SCHEMBL8326767 | 0.80 | DRD4 (0.47) | SIGMAR1 | |
| SCHEMBL8324185 | 0.80 | CHRM2 (0.39) | MAPTMITFALDH1A1HTTRAB9A | |
| SCHEMBL8329010 | 0.79 | CHRM2 (0.41) | MAPTMITFALDH1A1HTTRAB9A | |
| SCHEMBL8328869 | 0.79 | CHRM2 (0.44) | MAPTMITFALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |