Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.38 |
| ▸ | ADH5 | P11766 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8325950 | 0.90 | ADORA3 (0.46) | ADORA3TRPV1ALDH1A1LMNAHTT | |
| SCHEMBL7864235 | 0.85 | ADORA3 (0.38) | ADORA3TRPV1NPSR1CACNA1CMAPT | |
| SCHEMBL8327248 | 0.81 | ADORA3 (0.68) | ADORA3TRPV1ALDH1A1LMNATP53 | |
| SCHEMBL8323854 | 0.80 | ADORA3 (0.62) | ADORA3ALDH1A1LMNAALOX12HTT | |
| SCHEMBL8323850 | 0.80 | ADORA3 (0.62) | ADORA3ALDH1A1LMNAALOX12HTT | |
| SCHEMBL8327558 | 0.80 | ADORA3 (0.54) | ADORA3TRPV1ALDH1A1LMNANPSR1 | |
| SCHEMBL7869546 | 0.76 | ADORA3 (0.41) | ADORA3TRPV1ALDH1A1LMNAALOX12 | |
| SCHEMBL30357940 | 0.73 | CACNA1F (0.54) | ADORA3ALDH1A1LMNACACNA1CMAPT | |
| SCHEMBL7269131 | 0.73 | CACNA1F (0.54) | ADORA3ALDH1A1LMNACACNA1CMAPT | |
| SCHEMBL8330375 | 0.72 | ADORA3 (0.42) | ADORA3TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |