Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8324360 | 0.82 | HDAC4 (0.40) | CYP3A4ALOX15ALOX12ALDH1A1HDAC4 | |
| SCHEMBL8329176 | 0.81 | MEN1 (0.38) | CYP3A4ALOX15ALOX12CHRM2ADRA1A | |
| SCHEMBL8328722 | 0.81 | IDO1 (0.42) | HDAC4KDM4E | |
| SCHEMBL27506328 | 0.81 | ACP3 (0.41) | CYP3A4ALOX15CYP2D6TSHRCYP2C19 | |
| SCHEMBL8324964 | 0.76 | KDM4E (0.38) | CYP3A4ALOX15ALOX12CYP2C9TSHR | |
| SCHEMBL8324974 | 0.75 | KMT2A (0.40) | CYP3A4ALOX15ALOX12CHRM2ADRA1A | |
| Benzene SCHEMBL7084450 | 0.74 | HDAC4 (0.54) | CYP3A4ALOX15ALOX12TSHRALDH1A1 | |
| SCHEMBL8327275 | 0.73 | SLC6A4 (0.51) | CYP3A4CYP2D6CYP2C9TSHRCYP2C19 | |
| SCHEMBL8323402 | 0.72 | PBRM1 (0.50) | CYP3A4PKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL28077966 | 0.72 | SLC6A2 (0.47) | CYP3A4ADRA1ACYP2D6TSHRADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0948496-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDONE COMPOUNDS AND METHODS OF USE | Amgen inc. (US) | 1999-10-13 | — | — | EP | disclosed |
| WO-1998024780-A2 | SUBSTITUTED PYRIMIDINONE AND PYRIDINONE COMPOUNDS AND THEIR USE | AMGEN INC. (US) | 1998-06-11 | — | — | WO | disclosed |