Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323609 | 0.90 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL7849540 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8502142 | 0.84 | ACHE (0.54) | AGTR1AGTR2LTB4R2 | |
| SCHEMBL8328934 | 0.83 | CHRM1 (0.47) | — | |
| SCHEMBL8329353 | 0.80 | ICMT (0.43) | AGTR1AGTR2 | |
| SCHEMBL8329222 | 0.78 | ICMT (0.42) | AGTR1AGTR2 | |
| SCHEMBL8324163 | 0.78 | ICMT (0.45) | AGTR1AGTR2 | |
| SCHEMBL8322474 | 0.78 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL8330654 | 0.78 | ICMT (0.40) | AGTR1AGTR2 | |
| SCHEMBL9035257 | 0.77 | AGTR1 (0.52) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0498721-B1 | N-substituted quinoline derivatives, process for their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them | HOECHST MARION ROUSSEL INC (FR) | 1999-12-22 | — | — | EP | claimed |